Accelerating GLP-1 Peptides to Market Through Integrated Formulation & Analytical Development
GLP-1 peptide therapeutics are rapidly reshaping the treatment landscape for diabetes and obesity, increasing the need for robust formulation development and comprehensive analytical characterization strategies that enable safe, scalable, and market-ready drug products.
This on-demand session explores integrated approaches to GLP-1 peptide development, highlighting how formulation science and analytical strategy work together to accelerate CMC readiness and support regulatory success.
As programs progress from early development to commercialization, GLP-1 drug products present challenges related to stability, solubility, aggregation behavior, viscosity control, device compatibility, and manufacturability. This webinar examines practical, science-driven strategies to address these complexities through deliberate formulation design and rigorous analytical control.
The session covers contemporary formulation approaches, including rational excipient selection, fatty acid conjugation, incorporation of non-canonical amino acids, and optimization strategies for injectable delivery systems. Case references from marketed therapies such as liraglutide, semaglutide, and tirzepatide provide real-world development context.
A key focus is on advanced analytical characterization techniques—including LC–MS, SEC–MALS, surface plasmon resonance (SPR), peptide mapping, cell-based bioassays, and stability-indicating methods—and their role in defining Critical Quality Attributes (CQAs), supporting control strategies, and strengthening CMC documentation for global regulatory submissions.
This webinar is relevant for professionals across formulation R&D, analytical development, CMC, quality, and regulatory functions involved in peptide-based therapeutic programs.
Key Takeaways
- How formulation decisions influence Critical Quality Attributes (CQAs)
- How integrated analytical data supports robust control strategies
- How structured CMC approaches strengthen regulatory submissions and program readiness
Watch the on-demand webinar to explore how integrated formulation and analytical strategies can support efficient and scalable GLP-1 peptide development.